Rodolfo Paoletti Medal for Distinction in European Pharmacology awarded to EACPT Current and Past Presidents.

The Rodolfo Paoletti Medal for Distinction in European Pharmacology at the 2017 EACPT Congress in Prague has been presented to current EACPT President Professor Tabassome
Simon from Paris and EACPT Past-President Professor Gonzalo Calvo from Barcelona. The awards were presented by EPHAR Past-President Professor Thomas Griesbacher and EPHAR President-Elect Mojka Kržan.

Prof. Mojca KRŽAN, EPHAR, Prof. Tabassome Simon - EACPT and Prof. Thomas Griesbacher - EPHAR

Prof. Gonzalo Calvo - EACPT with Mojka Kržan. - EPHAR.

The Rodolfo Paoletti Medal for Distinction in European Pharmacology is named after Rodolfo Paoletti, first President of the Federation of European Pharmacological Societies (1990-1997). The medal was created by EPHAR in 2014 to honour distinguished pharmacologists who have achieved merits for the discipline of Pharmacology in Europe.

Tabassome Simon has since 2015 been the Chair of the European Association for Clinical Pharmacology and Therapeutics (EACPT). She is Professor of Clinical Pharmacology in the Department of Pharmacology, AP-HP, Saint-Antoine Hospital, Pierre and Marie Curie University (UPMC) in Paris, France. She is also Member of the Board of the National Union of University Hospital Pharmacologists, of the Research Committee of the French Society of Cardiology, the strategic committee of the Pierre et Marie Curie University (UPMC-Paris 06), and the Research committee for the cancer university Institute (IUC-Paris 06). Pr Simon is the Director of the Clinical Research platform of the East of Paris, including the Clinical Research Unit (URC-EST: http://www.urcest.chusa.upmc.fr/), the clinical Research Center, and the BioBank Research Center of UPMC-Paris 06 University. Currently, the clinical research platform coordinates several multicenter national and international studies throughout centers in France. Read more ... 

Gonzalo Calvo was President of the European Association of Clinical Pharmacology and Therapeutics (EACPT) from 2011 - 2015.Gonzalo Calvo is a consultant in Clinical Pharmacology at the Hospital Clinic of Barcelona and Associate Professor of Pharmacology at the University of Barcelona (UB). After receiving his medical degree, he specialized in Clinical Pharmacology at CSU Vall d’Hebron (1993) and became a doctor of medicine in 1997. Prof. Calvo’s main area of expertise is drug regulation, with particular interest in cardiovascular and onco-haematology. He has been principal investigator of around 50 clinical trials and has co-authored 85 peer-reviewed papers and 2 books. From 2002 to 2011, he represented the Spanish Agency on Medicines and Healthcare Products (AEMPS) at the EMA Committee for Human Medicinal Products (CHMP) as rapporteur of more than 60 new drug applications. Prof. Calvo has since 2013 been the co-chair of the European Medicines Agency Healthcare Professional Working Party. 

The Rodolfo Paoletti Medal for Distinction in European Pharmacology is named after Rodolfo Paoletti, first President of the Federation of European Pharmacological Societies (1990-1997). The medal was created by EPHAR in 2014 to honour distinguished pharmacologists who have achieved merits for the discipline of Pharmacology in Europe.

The 2019 EACPT Congress will be held in Stockholm and the 2021 EACPT Congress in Athens.

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.

2015 EACPT Scientific Award and Joint EACPT-EPHAR Translational Pharmacology Awards

The 12th biennial Congress of the European Association for Clinical Pharmacology and Therapeutics (http://eacpt.eu) was held in Madrid from 27th to 30th June 2015. Over 500 abstracts were accepted from 66 countries and from all 5 continents for presentation as e-posters and oral presentations. The 54 oral presentations were eligible for awards for best talks. The 2015 EACPT Scientific Award and Joint EACPT-EPHAR Translational Pharmacology Awards were presented at the end of June at the EACPT Congress in Madrid.

Listen to these 2015 EACPT Award winners discussing the research which led to their awards.


EACPT Scientific Award was conferred on UK Scientist Professor Nicholas Bateman for work on treating paracetamol overdose. The EACPT Scientific Award, which includes a prize of 2000€, was presented to Professor Bateman at the 12th EACPT Congress in Madrid in June 2015. 

The inaugural EACPT-EPHAR Young Investigator Awards in Translational Pharmacology have been conferred on PhD student Christoph Schneider from Bern in Switzerland and Dr Daniel Antoine from Liverpool in the UK.

Donald Singer (EACPT EC), Nicholas Bateman and Tabassome Simon (EACPT Chair)

Professor Bateman's research, which was published in the international medical journal The Lancet, involved a clinical trial comparing a new regimen to treat paracetamol poisoning with the current one (which has been used for over 40 years). It is the first large-scale, properly powered and randomised controlled clinical trial conducted in paracetamol poisoning, a challenging environment for trial work. 

The Federation of European Pharmacology Societies (EPHAR) and the European

Thomas Griesbacher (EPHAR President), Christoph Schneider, Dr Daniel Antoine, Tabassome Simon (EACPT Chair)

Association for Clinical Pharmacology and Therapeutics (EACPT) developed the above Young Investigator joint initiative to recognise projects of excellence in translational research in pharmacology. 2 awards of EUR 1,000 each were given EACPT Congress in Madrid to Christoph Schneider and Dr Daniel Antoine for their recent outstanding research papers. 

Requirements for the EACPT-EPHAR Young Investigator Awards in Translational Pharmacology are that applicants must be not more than 35 years of age on the deadline date, have as first author published an outstanding paper in the 2 years prior to the Awards, have conducted the submitted study in an institution of a country member of EACPT and/or EPHAR; and be a member of one of the member societies of EPHAR or EACPT, or be an individual associate member of EACPT.

Announcement of first joint EACPT-EPHAR Young Investigator Awards in Translational Pharmacology

The inaugural EACPT-EPHAR Young Investigator Awards in Translational Pharmacology have been conferred on PhD student Christoph Schneider from Bern in Switzerland and Dr Daniel Antoine from Liverpool in the UK.

The Federation of European Pharmacology Societies (EPHAR) and the European Association for Clinical Pharmacology and Therapeutics (EACPT) developed this joint initiative to recognise projects of excellence in translational research in pharmacology. There are 2 awards of EUR 1,000 each that will be given in 2015 to the above two young scientists for their recent outstanding research papers. 

Requirements for the Awards are that applicants must be not more than 35 years of age on the deadline date, have as first author published an outstanding paper in the 2 years prior to the Awards, have conducted the submitted study in an institution of a country member of EACPT and/or EPHAR; and be a member of one of the member societies of EPHAR or EACPT, or be an individual associate member of EACPT.

Christoph Schneider's award was for his paper The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites, which was published in the journal Science Translational Medicine in January 2015.

A systems biology approach was applied in this study to explore the human repertoire of IgG antibodies for binding 610 different biologically relevant glycan epitopes. Schneider conducted the data analysis using state-of-the-aart bioinformatics involving a range of programs, including the statistical computing graphic software environment “R”. Furthermore, Schneider conducted research involving full access to the consortium of functional glycomics array database as well as the bacterial carbohydrate structure database.

Christoph Schneider

Christoph Schneider's obtained his Master of Science in Biomedical Sciences from the University of Bern, Switzerland in 2013. Since then, he has been PhD student at the Institute of Pharmacology of the University of Bern, in the research-group of Stephan von Gunten (MD, PhD). Christoph Schneider gained previous insights into research as research assistant in Switerland at the ETH in Zurich as well as at Frimorfo AG in Marly. Currently, his research interests cover different fields of glycomics and immunology, such as the protein-carbohydrate interactions of immunoglobulins and of Siglec receptors, expressed on NK- and cytotoxic T cells. His research is based on in vitro techniques involving primary human leukocytes as well as human antibody-preparations and involves different analytical approaches, such as flow cytometry, glycan arrays, confocal microscopy and system level approaches.

Dr Daniel Antoine's award was for his paper Mechanistic Biomarkers Provide Early and
Sensitive Detection of Acetaminophen-Induced Acute Liver Injury at First Presentation to
Hospital published in August 2013 in the journal Hepatology. The main finding of this published study was that a panel of novel biomarkers linked to the mechanism of hepatotoxicity can report acute liver injury very early on in man, before currently
used clinical chemistry markers. This paper builds on his previous translational work in clinical and preclinical studies utilising this biomarker approach to define the mechanistic basis of acetaminophen-induced liver injury and to also predict prognosis. 

Dr Daniel Antoine

Dr  Antoine works in the MRC Centre for Drug Safety Science in the Department of. Molecular and Clinical Pharmacology at the University of Liverpool in the UK. Dr Daniel Antoine is currently a Wellcome Trust funded research fellow at the MRC Centre for Drug Safety Science (CDSS) and lecturer in Pharmacology at the University of Liverpool, UK. Dr Antoine completed his PhD in 2009 in Pharmacology. Prior to his PhD, Dr Antoine completed his B.Sc (Hons) in Biochemistry (first class) and worked in research posts within Molecular Toxicology at AstraZeneca. He undertook postdoctoral training at the CDSS with Prof BK Park and Prof M Pirmohamed as well as Royal Society International Travelling Fellowships at the Harvard Medical School, USA, with Prof JV Bonventre and at the Karolinska Institute, Sweden, with Prof U Andersson. Dr Antoine is currently the coordinator of the safety biomarker research group at the CDSS, Liverpool, UK. 

His research is mainly focused on the understanding of fundamental mechanisms related to adverse drug reactions and the prediction of drug toxicity through the development of translational biomarkers of drug-induced liver and kidney injury. He is a member of the DILI (drug-induced liver injury) project team for the SAFE-T (Safer And Evidence based Translation) IMI consortium to develop and qualify safety biomarkers. He also sits on the British Toxicology Society’s (BTS) Education, Training and Early Career Toxicologists Sub-Committee and is the co-chair of the British Pharmacological Society (BPS) Toxicology Affinity Group. In 2014, Dr Antoine was elected to serve as a Councillor for the International Union of Basic and Clinical Pharmacology (IUPHAR) Drug Metabolism and Drug Transport Section Executive Board. 

In 2013, Dr Antoine received the British Toxicology Society’s Early Career Investigator Award and in 2015 received the European New Investigator Award from the International Society for the Study of Xenobiotics (ISSX) and the 2015 Bill Bowman Travelling Lectureship from the British Pharmacological Society. Dr Antoine is an editorial board member for the journals Pharmacology Research & Perspectives and Biomarkers. Dr Antoine’s academic research is currently funded by grants awarded from the European Commission, Medical Research Council, Wellcome Trust, The Royal Society and the pharmaceutical industry.

The  joint EACPT-EPHAR Young Investigator Awards in Translational Pharmacology will be presented at an Awards Ceremony during the 12th EACPT Congress in Madrid - 27th - 30th June 2015 where both award winners will present their research findings.

Update from Kiel on the EACPT

The EACPT Executive Committee has been meeting in warm and sunny Kiel in

Altstadt - the old centre of Kiel

Northern Germany over the weekend of 10^th-11^th April, in advance of the 12th biennial Congress of the EACPT, to be held in Madrid from 27^th to 30^th June 2015.

The final programme was discussed for the 2015 EACPT Congress in Madrid. Over 500 abstracts have been accepted for presentation as e-posters and as 54 oral presentations, eligible for an award for the best talk.

EACPT EC Meeting at University in Kiel

The 12th EACPT Congress in 2015 is an unparalleled educational forum where you will learn about the newest developments, innovative techniques, and advanced practices in topics such as drug discovery, drug development, pharmacology and pharmacotherapy.
The Congress gives you the unique opportunity to network with top ranking specialists in pharmacology and pharmacotherapy, from around the world, and learn from the best. Reviews and commentaries from the Congress will be published in the EACPT Official Journal - Clinical Therapeutics.
The Congress will provide excellent formal and informal networking opportunities, supported after the Congress through the new website of the EACPT, due to be launched within the coming month.

There is to be launch of a new Associate Membership category for the EACPT, included within registration for the Madrid June 2015 Congress. Associate Members will have discounts on registration for EACPT Congresses and Focus Meetings, online access to the official EACPT journal Clinical Therapeutics, and many opportunities to become directly involved in networking with fellow clinical pharmacologists from throughout Europe and further afield.

Nominations were discussed for EACPT Awards to be presented at the 12^th EACPT Congress in Madrid. The EACPT Lifetime Award is for significant achievement in clinical pharmacology and therapeutics, both for the benefit of science and also for the benefit and health of the specialty, over a whole working life. The EACPT Scientific Award is awarded for the best scientific paper on a topic relevant to clinical pharmacology published by a European clinical pharmacologist in the two years between EACPT congresses. The EPHAR-EACPT award is by the Federation of European Pharmacology Societies (EPHAR) and the EACPT - a joint initiative to award the best work in translational research in pharmacology. There will be 2 awards of 1,000 € each, that will be given in 2015 to young scientists who have published an outstanding research paper in the past two years.
There were reports on interaction with other professional organisations and societies, including the European Medicines Agency, IUPHAR, the International Union of Pharmacology and EPHAR, the European Federation of Pharmacology Societies. Plans with EPHAR, in addition to the above awards, include a joint session on immunopharmacology during the Madrid Congress in June.
Calls were agreed for future EACPT Focus Meetings, with a deadline 31^st May 2015 for bids for summer 2016 and summer 2017. The 2017 meeting will be held in Prague as a Satellite Meeting of the 2017 EACPT Prague Congress
Bids were discussed in outline for the 2021 EACPT Congress, for which proposals from the Dutch Society for Clinical Pharmacology and the Hellenic Society of Basic and Clinical Pharmacology have been short-listed. The 2017 EACPT Congress will be held in Prague and the 2019 EACPT Congress in Stockholm.
Register for the EACPT Congress in Madrid – 27th-30th June 2015
Clinical Therapeutics -  Official Journal of the EACPT
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Listen to podcasts from the latest EACPT Congress in Geneva
2013 EACPT Lifetime Award winner Professor Carlo Patrono on platelets, cardiovascular risk & cancer


Podcasts with speakers at the 2013 EACPT Congress in Geneva
- Patrick Mismetti on clinical drug development of new anticoagulants
- Tabassome Simon discusses Clinical Pharmacology and the FAST-MI Registry
- Tabassome Simon discusses the origins and importance of the FAST-MI Registry
- EACPT Congress keynote lecturer Ziad Mallat discusses developing a clinical research career
- EACPT Congress keynote lecturer Ziad Mallat discusses immunotherapy against vascular disease


Comments from delegates on the 2013 EACPT Congress in Geneva
- Swiss Delegates from Zurich and Basel
- Jelena Vukovic from Serbia & Marija Bosilkovska from Geneva
- George Dugbartey and Sorayeh Moradi
- Sarawut Jindarat from Thailand
- Yukari and Ryuichi Ogawa from Tokyo
- Kristina Münch and Barbara Pfistermeister from Germany
- Lada Leyens from Switzerland