2019 EACPT Scientific Award goes to David Brinkman for paper on CPT education

Congratulations to David Brinkman from the Department of Internal Medicine at the VU University Medical Centre in Amsterdam who has won 2019 EACPT Scientific Award for the best scientific paper on a clinical pharmacology or therapeutic theme in the previous 2 years.

His winning paper on “Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study” was published in Clinical Pharmacology and Therapeutics [2018;104:317-325]. Dr Brinkman will receive the EACPT Scientific Award on Tuesday 2nd July during the 14th biennial EACPT Congress in Stockholm.

David Brinkman was the first author of the report, which he co-authored with international colleagues from the Education Working Group of the European Association for Clinical Pharmacology and Therapeutics (EACPT) and its affiliated Network of Teachers in Pharmacotherapy.

Recent studies had reported both that the prescribing competencies of final-year medical students in Europe were poor, which if happening in clinical practice could result in potentially harmful prescribing errors; and that there is marked variation in CPT education within and between European countries.

In the paper, key learning outcomes were identified for teaching and assessing CPT in undergraduate medical curricula in Europe.

A large European expert panel reached consensus on 252 key learning outcomes that should be included in undergraduate CPT curricula to ensure that European graduates are able to prescribe safely and effectively. The panel also provided a blueprint of a European core curriculum in CPT, including key learning outcomes and how they might be taught and assessed during undergraduate medical training.

The paper concluded that a European core curriculum in CPT might help to harmonize CPT education and improve the prescribing competencies of future European doctors and thereby patient safety.

EACPT Congress will be held from 29th June to 2nd July in 2019 in Stockholm as a partnership between the EACPT and the Swedish Society for Pharmacology, Clinical Pharmacology and Therapeutics. 

Opportunities for EACPT Associate Members include
* discounted registration fees for EACPT meetings
* networking with colleagues worldwide through the global EACPT network of Associate Members
* active involvement in EACPT Working Parties and other activities 

Find out how to become an Associate Member of the EACPT 

Future EACPT Congresses will be held in:
- 2021 Athens
- 2023 Rotterdam

The EACPT was founded in 1993 and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Pharmacology and therapeutics education in the EU needs harmonisation and modernisation

The EACPT has supported a European study of clinical pharmacology and therapeutics education which has now just been published in the journal Clinical Pharmacology & Therapeutics.

Effective teaching in pharmacology and clinical pharmacology and therapeutics (CPT) is necessary to make medical students competent prescribers. However, the current structure, delivery and assessment of CPT education in the European Union (EU) is unknown. 

In this study, the authors evaluated the current structure, delivery and assessment of clinical pharmacology and therapeutics education in the European Union. The authors conclude from a cross-sectional survey among 185 medical schools in 27 countries that pharmacology and therapeutics education in the EU needs harmonisation and modernisation. 

The manuscript is now freely accessible as an abstract and as a full paper through the journal.

The next EACPT Congress is to be held in Prague from 24-27 June 2017.

Register for the Prague Congress

Charles Bridge, Prague

-  22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines  

- almost 500 oral and poster presentations from the European Region and around the world  

- presentation of EACPT Lifetime Achievement (Professor Pertti J.Neuvonen, Finland) and Scientific Awards 

- opportunity to network with global experts and trainees in the fields of research, clinical practice, the biotechnology sector, regulation and health policy  

- update on the activities of the EACPT Working Groups for Research, Education, Regulation and Young Pharmacologists.

More on the Prague Congress

Click here to apply online for EACPT membership

Anyone from anywhere in the world with a professional interest in clinical pharmacology and/or therapeutics can now join the EACPT as an Individual Associate member. 

There are reduced joining fees for Individual Associate members who are already members of a national or international organisation relevant to clinical pharmacology and therapeutics.

Register for updates on safety and effectiveness of medicines at EACPT Prague Congress - 24-27 June 2017

Rotterdam 7th April, 20017

The EACPT Executive Committee are meeting in Rotterdam to agree final details of the next EACPT Congress to be held in Prague from 24-27 June 2017.

Register for the Prague Congress

Early registration deadline 17 April

Standard registration deadline 16 June

Highlights of the Congress will include

-  22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines  

- almost 500 oral and poster presentations from the European Region and around the world  

- presentation of EACPT Lifetime Achievement (Professor Pertti J.Neuvonen, Finland) and Scientific Awards 

- opportunity to network with global experts and trainees in the fields of research, clinical practice, the biotechnology sector, regulation and health policy  

- update on the activities of the EACPT Working Groups for Research, Education, Regulation and Young Pharmacologists.

 

Charles Bridge - Prague

More on the Prague Congress

The programme will provide an international scientific and educational forum for discussion of clinical pharmacology and therapeutics, including personalised pharmacotherapy.

Themes will include the latest developments on effectiveness and safety of medicines, clinical pharmacology in clinical practice, pharmacokinetics/systems pharmacology, including in special populations, innovative techniques, eHealth, biomarkers, education, advanced practices in topics such as drug discovery, drug development, biological therapies, global health with a focus on access to safe medicines, new pharmacology and pharmacotherapy, safety in prescribing and updates on personalised medicines, as well as updates on specific therapeutic areas, including cardiovascular disease, infectious disease, nephrology, oncology, neurology and psychiatry.

Click here to apply online for EACPT membership. 

Anyone from anywhere in the world with a professional interest in clinical pharmacology and/or therapeutics can now join the EACPT as an Individual Associate member. 

There are reduced joining fees for Individual Associate members who are already members of a national or international organisation relevant to clinical pharmacology and therapeutics.

Membership benefits include:

* Access to videos of talks from EACPT Meetings

* Discounted registration fees for EACPT meetings

* Online access to the Official EACPT Journal - Clinical Therapeutics

* Access to the EACPT’s worldwide network of Individual Associate Members

* Active involvement in EACPT

The 2019 EACPT Congress will be held in Stockholm and the 2021 EACPT Congress in Athens.

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.

2017 EACPT Lifetime Achievement Award to go to Professor Pertti Neuvonen from Finland

The EACPT is  delighted to announce that the 2017 Lifetime Achievement Award of the European Association of Clinical Pharmacology and Therapeutics will go to Professor Pertti J. Neuvonen from Finland for his outstanding contribution to the national and international benefits of clinical pharmacology for medicine, health care and patient safety.

The Award, which includes the EACPT silver medal, will be presented to Professor Neuvonen during the 13th EACPT Congress in Prague. The Congress runs from 24th - 27th June 2017.

Professor Emeritus Pertti J. Neuvonen

Professor Emeritus Pertti J. Neuvonen, whose research focuses on drug safety and individual variability in drug response, particularly on drug interactions and their mechanisms, is one of the most cited clinical pharmacologists in the world, with over 20,000 citations. He has been listed by Thomson Reuters for years as an ISI Highly Cited Researcher in Pharmacology. He has authored over 500 original articles and reviews. Of the original papers, 92 have been published in the journal Clinical Pharmacology & Therapeutics. He has supervised around 50 Doctoral (PhD) thesis projects. 

Since 1970, Neuvonen´s research group has found more than 200 previously unrecognized, clinically important drug-drug interactions and several significant food-drug interactions. Furthermore, his group demonstrated, already in the 1980-90s, the efficacy of activated charcoal as gastric decontaminator, compared with induced emesis and gastric lavage. The drug interaction studies in humans were deepened by in vitro studies to explore mechanism, predictability and avoidance of the interactions. His group observed that inhibition and induction of CYP3A4/5-enzyme could cause over 10-fold changes in exposure to several drugs (midazolam, triazolam, buspirone, felodipine, simvastatin, lovastatin). 

Furthermore, his group discovered among generally used drugs many previously unrecognized inhibitors of drug metabolism (itraconazole: CYP3A4; gemfibrozil and clopidogrel: CYP2C8) and unexpected victim substrates (tizanidine: CYP1A2; cerivastatin, repaglinide, pioglitazone, rosiglitazone, loperamide, montelukast: CYP2C8). In addition to drug metabolizing enzymes, also membrane transporters (e.g., OATP1B1, P-glycoprotein, BCRP), and their pharmacogenetics and interactions were found to affect pharmacokinetics (e.g., statins) and drug response. Many of the original findings made by Neuvonen and his research groups have been adopted into textbooks, guidelines (e.g., FDA) and product information texts.

Pertti Neuvonen was born in Kirvu (Finland) on 25. August 1943. He is married and has five adult children. He studied medicine at the University of Helsinki between 1964 and 1970, and defended his doctoral thesis at this University in 1971. From 1971 to 1972, he was as a fellow of the Alexander von Humboldt-Foundation in Hannover Medical School (Germany). From 1972-1985, he was Senior Lecturer/Assistant Professor/Consultant of Clinical Pharmacology, and from 1986-1988 Acting Professor and Head Physician of Clinical Pharmacology at University of Helsinki and University Central Hospital, including the National Poison Information Centre. Between 1988 and 1991, he was Professor and Chairman of Pharmacology at University of Turku. From 1992 to 2011, he was Professor and Head of Clinical Pharmacology at University of Helsinki and University Central Hospital. After his retirement in 2011, he continues his studies at the Department of Clinical Pharmacology as a free researcher. In 2011, he received the BCPT Nordic Prize in Basic & Clinical Pharmacology & Toxicology, and the Medal of the FDA Office of Clinical Pharmacology.

The EACPT was founded 24 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Submit abstracts for "How to Assess Medicines from Research to Clinical Practice": 6-9 October 2016. EACPT Focus Meeting - Opatija, Croatia.

The next EACPT Focus Meeting will be held from 6th to 9th October, 2016 in partnership with the Croatian Society for Clinical Pharmacology and Therapeutics.

The theme of the meeting is “How to Assess Medicines from Research to Clinical Practice”.

There will be a bursary fund of 10,000 € to support abstract presenters.

See meeting programme

Key dates

Abstract Submission Deadline - June 15, 2016

Early Registration Deadline - June 30, 2016

Online Meeting Registration Deadline - September 30, 2016  

 

The main objectives of this Focus Meeting are to increase awareness, knowledge and use of critical assessment pillars for medicinal products in everyday clinical practice in order to improve healthcare outcomes in affordable manner.

The meeting will include a combination of scientific podium lectures, interactive workshops and guided poster sessions covering three main pillars important for the critical assessment of medicinal products - efficacy, effectiveness, and economics (3E assessment).

There will be a dedicated session for Young Pharmacologists during the meeting. There will be an EACPT Scientific Communication Award for the best presentation by a young scientist. 

Confirmed speakers and topics

JANNE TAPIO BACKMAN (Finland): Clinical drug-drug interaction studies: methods, pitfalls and interpretation

NADA BOŽINA (Croatia): The role of pharmacogenetics in individulized treatment choices

YLVA BOTTIGER (Sweden): National model for the introduction and follow-up of new, expensive drugs in Sweden

GONZALO CALVO (Spain): Accelerated approval paths. What they do mean and what they should not mean?

SIMON MAXWELL (UK): Safe introduction of new medicines into clinical practice

KEN PATERSON (UK): Rapid Health Technology Assessment of New Medicines - Lessons from 15 Years Experience in Scotland

WORKSHOP 2: EXCELLENCE IN CLINICAL RESEARCH - CLINICAL TRIAL DESIGN

IGOR FRANCETIĆ (Croatia): Effectiveness assessment: when pharmacokinetics makes a difference / macrolide and azalide examples

MATTHIAS SCHWAB (Germany): Pharmacogenomics and drug response: future challenges

EDUARDO SPINA (Italy): Efficacy of antidepressants: issues related to bias in clinical trials

TABASSOME SIMON (France): Key points for building succesful clinical trial

SINIŠA TOMIĆ (Croatia): The Role of the National Competent Authority (NCA) in the Assessment of Medicinal Products in the National Procedure

DONALD SINGER (UK): Personalised medicine approaches for identifying effective therapies

SLOBODAN VUKIČEVIĆ (Croatia): Current challenges and hurdles in new drug development

We will be guests in the Adriatic coastal town Opatija, Croatia. Opatija lies at the centre of the Kvarner Riviera with the longest tradition of providing quality conference venues in Croatia. Opatija’s very attractive geographic location, lush green scenery and a pleasant climate (45° 20’ north latitude) were some of the main reasons for its origins and the rapid development of its tourism from the end of the 19th century.  The venue – Grand Hotel 4 Opatijska Cvijeta –  is located in the very centre of Opatija and includes four buildings that were named after Opatija’s best-known flowers. The hotel has 223 rooms. The hotel also includes the large Tamaris congress centre, which has 7 multi-functional halls and the latest congress equipment.

Anyone from anywhere in the world with a professional interest in clinical pharmacology
and therapeutics can now join the EACPT as an Individual Associate member.
Membership benefits include:

• Access to videos of talks from EACPT Meetings

• Discounted registration fees for EACPT meetings

• Online access to the Official EACPT Journal - Clinical Therapeutics

• Access to the EACPT’s worldwide network of Individual Associate Members

• Active involvement in EACPT 

The EACPT was founded 24 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Meet members of the new EACPT Board of International Consulting Editors

A meeting of members of the EACPT Board of International Consulting Editors (BICE) was held during the EACPT Congress in Madrid. The 12th biennial Congress of the European Association for Clinical Pharmacology and Therapeutics (http://eacpt.eu) was held in Madrid from 27th to 30th June 2015. Over 500 abstracts were accepted from 66 countries and from all 5 continents for presentation as e-posters and oral presentations. 54 oral presentations were eligible for best talk awards.

Hear from some of the EACPT BICE members: Jozef Glasa (Slovak Republic), Romuald Bellman (Austria), Sinem Ezgi Gulmez (France), Alexander Khokhlov (Russia) and Dr Marie Besson (Switzerland) in discussion with Donald Singer (EACPT). 

The official journal of the EACPT is Clinical Therapeutics, published by Elsevier: Editor-in-Chief - Dr Richard Shader 

Full list of EACPT BICE members:
- Romuald Bellman, Innsbruck Medical University, Innsbruck, Austria 
- Marie Besson, Geneva University Hospitals, Switzerland 
- Bernard Cheung, Queen Mary Hospital, Hong Kong 
- Emilio Clementi, University of Milan, Italy 
- Jozef Glasa, Slovak Medical University, Bratislava, Slovakia 
- Sinem Ezgi Gulmez, University of Bordeaux, France
- Maria Theresa Herdeiro, University of Aveiro, Portugal 
- Alexander Khokhlov, Clinical Hospital, Yaroslavl State Medical University, Russia 
- Adrián Llerena, Clinical Research Center University Hospital, Badajoz, Spain 
- Stefan Oswald, University of Greifswald, Germany

Madrid EACPT Masterclass by EACPT official journal editor Richard Shader on how to publish in scientific journals

The 12th biennial Congress of the European Association for Clinical Pharmacology and Therapeutics (http://eacpt.eu) was held in Madrid from 27th to 30th June 2015. Over 500 abstracts were accepted from 66 countries and from all 5 continents for presentation as e-posters and oral presentations. the 54 oral presentations were eligible for an award for the best talk. 

At a well-attended EACPT Congress session, EACPT official journal editor Richard Shader gave a Masterclass to over 80 delegates on how publish a scientific paper.

Listen to Dr Shader discussing Clinical Therapeutics with Donald Singer from the EACPT:

Dr Shader's key messages on scientific writing included

- write clearly
- explain why you undertook the work
- describe how you advanced knowledge in the field.
- note further work that would take the field forward
- decide title and write abstract last - avoid excessive use of adverbs  
 - use short sentences
- consider use of translation support if English is not your first language: this should be translation of your own text, NOT ghost writing

More helpful advice for authors

The European Association of Clinical Pharmacology and Therapeutics has Clinical Therapeutics as its Official Journal, in partnership with the major international publisher Elsevier. 

The journal features highlights of EACPT scientific and other activities and provides information on future EACPT congresses, summer schools and other events. The journal  also publishes peer-reviewed original papers and reviews arising from EACPT conferences. 

More from EACPT Madrid 2015: Addressing heteregeneity in treatment response

The 12th biennial Congress of the European Association for Clinical Pharmacology and Therapeutics (http://eacpt.eu) is underway in Madrid from 27th to 30th June 2015. Over 500 abstracts have been accepted from 65 countries and from all 5 continents for presentation as e-posters and oral presentations. the 54 oral presentations are eligible for an award for the best talk. 

Listen to Caridad Pontes (Barcelona) and Marie Besson (Geneva) discussing implications for regulators, clinical trialists and patients of increasing recognition of variable patient responses to their medicines.

Trainee Clinical Pharmacologists in Madrid for the 12th EACPT Congress

The 12th biennial Congress of the European Association for Clinical Pharmacology and Therapeutics (http://eacpt.eu) is being held in Madrid from 27th to 30th June 2015. Over 500 abstracts have been accepted from 66 countries and form all 5 continents for presentation as e-posters and oral presentations. the 54 oral presentations are eligible for an award for the best talk. 

At a pre-congress session, Clinical Pharmacologists in training met to discuss professional and training issues and ways in which involvement with the EACPT may be helpful.

Lucio Ghiglione, Alexandra Pelaez Rivas and colleagues

Petru Micliuc and colleagues

Delegates from France, UK, Portugal, Denmark and South Korea

BPS warns more clinical pharmacologists needed to improve health of patients and save money

The British Pharmacological Society has launched a report calling for an increase in the number of clinical pharmacologists across the United Kingdom. Clinical Pharmacology is the only specialty that focuses on the safe, effective and economic use of medicines. The discipline is well placed to help the NHS to overcome major current and expected clinical and economic challenges.

The key messages in this report about the importance of Clinical Pharmacology for patient health and cost-effective medicine are also very relevant to patients, health professionals and health systems across the European Union and around the world.

Read more about the report

Read the report

See media coverage of the report

Update on the 12th European Association for Clinical Pharmacology and Therapeutics Congress in Madrid: 27-30 June, 2015

Madrid is the hosting city for the 12th Congress of the European

Habsburg period Plaza Mayor, Madrid

Association for Clinical Pharmacology and Therapeutics, to be held June 27-30, 2015
at the Hotel Meliá Castilla, in the heart of Madrid.
EACPT Congresses attract a worldwide audience. It is the first time the EACPT Congress will take place in Spain.

Our EACPT Congress in Madrid 2015 is being organised in close collaboration between the EACPT and the Spanish Society of Clinical Pharmacology (SEFC).
A key aim of the Congress is to continue the work of the EACPT to strengthen the impact of our discipline across Europe and to make the EACPT both the common home of European Clinical Pharmacologists and a worldwide reference point for professionals in the field. 
This Congress will include contributions from our Portuguese and Latin American colleagues to give this meeting a special intercontinental flavour. 


View the outline scientific program

Abstract submission now open - deadline 3 February 2015

Registration opens soon - Early registration deadline 31 March 2015

SEE YOU ALL IN MADRID!

The official journal of the EACPT is Clinical Therapeutics