New bio-therapies for heart failure discussed at EACPT 2017 in Prague

The EACPT 2017 Congress was held in Prague from 24th-27th June with 566 participants from all 5 continents - 28% from beyond the European Region, from Australia to China, Japan and South Korea to the USA. The Congress included 22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines.

Heart Failure (HF) is a leading cause of death and disease in Europe. Its prevalence will continue to increase worldwide with the ageing of populations and increasing adoption of “Western” lifestyles in less developed countries. Congestive HF is the final consequence of a wide range of disorders of the heart and circulation, including hypertension, atherosclerosis, cardiomyopathy and heart valve disease.

Professor Jean-Sébastien Hulot

Despite progress in treatments with conventional medicines and devices, there remains a need for new approaches to reverse severity and progression on ventricular dysfunction.

Through an active collaboration with the Cardiovascular Research Center at Mount Sinai School of Medicine in New York (Director Prof. Hajjar) the team of Professor Jean-Sébastien Hulot in Paris is involved in the development of new targeted molecular therapies for heart failure.

In the video below you can hear Professor Hulot discuss highlights from his EACPT Prague keynote lecture on gene therapy and other new bio-therapies for heart failure.

Future EACPT Congresses:

- 2019 Stockholm

- 2021 Athens

- 2023 Rotterdam

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.

Major awards presented at EACPT Congress in Prague

Prof. Neuvonen

The EACPT 2017 Congress was held in Prague from 24th-27th June with 566 participants from all 5 continents - 28% from beyond the European Region, from Australia to China, Japan and South Korea to the USA. The Congress included 22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines. Almost 500 oral and poster presentations will be presented by delegates from the European Region and around the world.

The 2017 EACPT Lifetime Achievement Award was presented to Professor Pertti J. Neuvonen, Finland for his outstanding contribution to the national and international benefits of clinical pharmacology for medicine, health care and patient safety.
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Prof  Calvo  with Prof. Kržan.

 Rodolfo Paoletti Medal for Distinction in European Pharmacology at the 2017 EACPT Congress in Prague was presented on 25th June to current EACPT President Professor Tabassome Simon from Paris and EACPT Past-President Professor Gonzalo Calvo from Barcelona. 

Prof. Kržan, Prof. Simon and Prof.Griesbacher

The awards were announced by EPHAR Past-President Professor Thomas Griesbacher and EPHAR President-Elect Mojka Kržan.

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Prof. Simon, Prof Webb and Prof. Böttiger

The EACPT Scientific Award was presented to Professor David Webb, President of the British Pharmacological Society for his 2015 Lancet paper on PATHWAY 2.  This study
reported a significant improvement in blood pressure control in older, overweight patients with poorly controlled hypertension despite combination medical therapy when the mineralocorticoid antagonist spironolactone was added, treatment supported by directly observed therapy.

Prof. Hiley, Prof. Böttiger, Dr. Schirris and Prof. Simon

EACPT-EPHAR Awards were presented by EPHAR President Robin Hiley, EACPT Immediate Past-Chair Tabassome Simon and EACPT Chair Ylva Böttiger.

Dr Tom Schirris received his EACPT-EPHAR Award for his work on novel off-targeting of statins to understand contributory factors in risk of statin induced muscle damage.

Profs. Hiley, Böttiger, Rongen and Simon.

Dr Hoeke Baarsma received his EACPT-EPHAR Award for work on WNT-5A as a novel target to inhibit as a potential way to recover alveolar function and thus reduce development and severity of emphysema in COPD. Prof. Gerard Rongen accepted the award on behalf of Dr Baarsma.

Dr Samer, Prof. Maxwell and Education colleagues

The award of the EACPT Education Working Group went to Professor Simon Maxwell from Edinburgh for his national and international work on improving education of future and current prescribers.

 

 Future EACPT Congresses: 

- 2019 Stockholm
- 2021 Athens
- 2023 Rotterdam

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.

Update from the EACPT Executive Committee meeting in Prague

The EACPT 2017 Congress was held in Prague from 24th-27th June with 566 participants from all 5 continents - 28% from beyond the European Region, from Australia to China, Japan and South Korea to the USA. The Congress included 22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines. Almost 500 oral and poster presentations will be presented by delegates from the European Region and around the world.

During the Congress, new EACPT Chair Professor Ylva Böttiger from Sweden led the first meeting of the renewed EACPT Executive Committee, voted in by Council members from the 32 national member societies affiliated to the EACPT.Key issues for discussion included

Key matters for discussion included

- future EACPT Congresses - the next due to be held in 2019 in Stockholm as a partnership between the EACPT and Swedish Society for Pharmacology, Clinical Pharmacology and Therapeutics

- EACPT working groups on Education, Research, Young Professionals, and Regulation and Ethics

- opportunities for Individual Associate Members

- new content for members on the EACPT website

The EACPT Executive Committee meets 6 monthly, with regular interim discussions by teleconference on key EACPT strategy and activities

Committee members from Austria, France, Italy, the Netherlands, the UK, Switzerland, Sweden and Finland.

 Future EACPT Congresses: 

- 2019 Stockholm
- 2021 Athens
- 2023 Rotterdam

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.

Experts at the EACPT Prague Congress discuss Global Health and Access to Safe Medicines

The EACPT 2017 Congress was held in Prague from 24th-27th June with 566 participants from all 5 continents - 28% from beyond the European Region, from Australia to China, Japan and South Korea to the USA. The Congress included 22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines.  

 

Access to Medicines (ensuring the supply chain for access to safe and effective medicines), is a high priority for health professionals, patients and health policy makers and funders within the European and global health perspective. The aim of the session at the EACPT Congress on this theme was to understand challenges and solutions for access to safe and effective medicines.

Panel speakers discuss highlights from the session in the video below.

Pavle Zelic, Jozef Glasa, Mike Isles and Donald Singer

Objectives

1. To understand which organisations and individual categories of health professional are responsible for protecting patients from exposure to unsafe and ineffective medicines.

2. To understand potential weaknesses in the supply chain of medicines from production to dispensing.

3. To be aware of the risks to patients from accessing medicines from unreliable sources, including from unsafe internet 'pharmacies’ and unregulated “healers”.

Speakers and themes

1. Securing the supply chain of medicines: whose responsibility?

Mike Isles, Executive Director,

European Alliance for Access to Safe Medicines

2. Challenges and solutions for policy makers for access to medicines

Professor Jozef Glasa, Institute of Pharmacology, Clinical and Experimental Pharmacology and Institute of Health Care Ethics, Slovak Medical University in Bratislava 

3. Fight against falsified medicines: coordinated actions at EDQM level through the Medicrime Convention

Pavle Zelic, International Cooperation, European Integrations and Public Relations Manager, Medicines and Medical Devices Agency of Serbia

EACPT 2017 Congress underway in Prague

The EACPT 2017 Congress is underway in Prague from 24th-27th June with 566 participants from all 5 continents - 28% from beyond the European Region, from Australia to China, Japan and South Korea to the USA.

Professor Pertti J. Neuvonen

The Congress includes 22 sessions with Keynote Lectures on current issues for research, education and clinical practice on safe and effective use of medicines. 

Almost 500 oral and poster presentations will be presented by delegates from the European Region and around the world  

During the opening session on Saturday 24th June, the 2017 EACPT Lifetime Achievement Award was presented to Professor Pertti J. Neuvonen, Finland. 

Paoletti Medal Awards

The Rodolfo Paoletti Medal for Distinction in European Pharmacology at the 2017 EACPT Congress in Prague was presented on 25th June to current EACPT President Professor Tabassome Simon from Paris and EACPT Past-President Professor Gonzalo Calvo from Barcelona. The awards were announced by EPHAR Past-President Professor Thomas Griesbacher and EPHAR President-Elect Mojka Kržan.

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Further scientific Awards will be presented later during the Congress.

During the Congress, delegates will have the opportunity to network with global experts and trainees in the fields of research, clinical practice, the biotechnology sector, regulation and health policy. There will also be updates on the activities of the EACPT Working Groups for Research, Education, Regulation and Young Pharmacologists.

More on the Prague Congress

Future EACPT Congresses:
- 2019 Stockholm
- 2021 Athens
- 2023 Rotterdam
 
The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.
Clinical Therapeutics, the Official Journal of EACPT.

Rodolfo Paoletti Medal for Distinction in European Pharmacology awarded to EACPT Current and Past Presidents.

The Rodolfo Paoletti Medal for Distinction in European Pharmacology at the 2017 EACPT Congress in Prague has been presented to current EACPT President Professor Tabassome
Simon from Paris and EACPT Past-President Professor Gonzalo Calvo from Barcelona. The awards were presented by EPHAR Past-President Professor Thomas Griesbacher and EPHAR President-Elect Mojka Kržan.

Prof. Mojca KRŽAN, EPHAR, Prof. Tabassome Simon - EACPT and Prof. Thomas Griesbacher - EPHAR

Prof. Gonzalo Calvo - EACPT with Mojka Kržan. - EPHAR.

The Rodolfo Paoletti Medal for Distinction in European Pharmacology is named after Rodolfo Paoletti, first President of the Federation of European Pharmacological Societies (1990-1997). The medal was created by EPHAR in 2014 to honour distinguished pharmacologists who have achieved merits for the discipline of Pharmacology in Europe.

Tabassome Simon has since 2015 been the Chair of the European Association for Clinical Pharmacology and Therapeutics (EACPT). She is Professor of Clinical Pharmacology in the Department of Pharmacology, AP-HP, Saint-Antoine Hospital, Pierre and Marie Curie University (UPMC) in Paris, France. She is also Member of the Board of the National Union of University Hospital Pharmacologists, of the Research Committee of the French Society of Cardiology, the strategic committee of the Pierre et Marie Curie University (UPMC-Paris 06), and the Research committee for the cancer university Institute (IUC-Paris 06). Pr Simon is the Director of the Clinical Research platform of the East of Paris, including the Clinical Research Unit (URC-EST: http://www.urcest.chusa.upmc.fr/), the clinical Research Center, and the BioBank Research Center of UPMC-Paris 06 University. Currently, the clinical research platform coordinates several multicenter national and international studies throughout centers in France. Read more ... 

Gonzalo Calvo was President of the European Association of Clinical Pharmacology and Therapeutics (EACPT) from 2011 - 2015.Gonzalo Calvo is a consultant in Clinical Pharmacology at the Hospital Clinic of Barcelona and Associate Professor of Pharmacology at the University of Barcelona (UB). After receiving his medical degree, he specialized in Clinical Pharmacology at CSU Vall d’Hebron (1993) and became a doctor of medicine in 1997. Prof. Calvo’s main area of expertise is drug regulation, with particular interest in cardiovascular and onco-haematology. He has been principal investigator of around 50 clinical trials and has co-authored 85 peer-reviewed papers and 2 books. From 2002 to 2011, he represented the Spanish Agency on Medicines and Healthcare Products (AEMPS) at the EMA Committee for Human Medicinal Products (CHMP) as rapporteur of more than 60 new drug applications. Prof. Calvo has since 2013 been the co-chair of the European Medicines Agency Healthcare Professional Working Party. 

The Rodolfo Paoletti Medal for Distinction in European Pharmacology is named after Rodolfo Paoletti, first President of the Federation of European Pharmacological Societies (1990-1997). The medal was created by EPHAR in 2014 to honour distinguished pharmacologists who have achieved merits for the discipline of Pharmacology in Europe.

The 2019 EACPT Congress will be held in Stockholm and the 2021 EACPT Congress in Athens.

The EACPT was founded 25 years ago and now includes as members all national organisations for clinical pharmacology in Europe, as well as organisations from further afield internationally. The EACPT aims to provide educational and scientific support for the more than 4000 individual professionals interested in clinical pharmacology and therapeutics throughout the European region, with its congresses attended by a global audience. The EACPT also advises policy makers on how the specialty can contribute to human health and wealth.

Clinical Therapeutics, the Official Journal of EACPT.